Endocrine Abstracts

Paraganglioma (PGL) are rare neuroendocrine tumors with an estimated prevalence of 1:6500, with cardiac PGL being even rarer. Although most PGL are benign, approximately 15–35% of PGLs have metastatic disease, with few effective treatment options. Novel therapeutic indications, such as 177Lu-DOTA-TATE for patients with PGL, has been investigated in several clinical trials. A 66-year-old woman was referred to Cardiology in 2011 due to an incidentaloma adjacent to the right...

Introduction: The differential diagnosis of overgrowth includes constitutional tall stature, excess growth hormone (GH) and genetic syndromes. Sotos syndrome generally presents with overgrowth, dysmorphisms and early learning disabilities. Here in, we describe the diagnostic pathway of Sotos Syndrome in an adult male presenting with tall stature and mild morphological and cognitive features, prompted by his son’s clear manifestation of the classic triad.<p class="abst...